Best Longevity Blood Tests of 2026: 4 At-Home Services We Compared Head to Head
If you want to track the biomarkers that actually predict how long and how well you live, the best longevity blood test for most people in 2026 is Superpower, which screens 100+ biomarkers for around $199 a year. Below we break down four leading at-home services so you can match the right panel to your budget and goals.
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Key Takeaways
- Superpower offers the most biomarkers per dollar for general longevity tracking, screening 100+ biomarkers for about $199 per year with a physician-reviewed dashboard.
- Function Health is the premium choice for people who want clinician sign-off and two full panels a year, covering 160+ lab tests for around $365 annually.
- For a single targeted question like thyroid or hormones, a one-off Everlywell kit ($49 to $299) costs far less than any annual membership and ships to your door.
A quick look at our top picks
- Best overall value: Superpower
- Best premium membership: Function Health
- Best for single targeted panels: Everlywell
- Best for frequent low-cost retesting: SiPhox Health
Comparison table
| Service | VST score (out of 5) | Price | Best for |
|---|---|---|---|
| Superpower | 4.7 | ~$199/year | Overall longevity value |
| Function Health | 4.5 | ~$365/year | Premium, clinician-reviewed |
| Everlywell | 4.2 | $49 to $299/kit | Single targeted panels |
| SiPhox Health | 4.1 | from ~$125 | Frequent low-cost retesting |
Superpower – Best for overall longevity value
Superpower is our top pick because it packs 100+ biomarkers, a blood draw, and a physician-reviewed dashboard into a membership that costs about $199 a year. For most people who want a yearly longevity baseline without paying premium prices, nothing else delivers as many markers per dollar.
Pros
- 100+ biomarkers covering heart, metabolic, hormone, thyroid, and inflammation markers in one panel
- Roughly $199 per year, the lowest annual price among full-membership services we reviewed
- At-home kit plus a lab draw, with a physician-reviewed dashboard and 17 health scores
- HSA and FSA eligible
Cons
- The base price is $399 per year for members in New York and New Jersey
- Supplement recommendations can nudge you toward extra spending, so treat them as optional
- One full panel per year rather than two
The membership starts you off with a full blood panel and turns the raw numbers into 17 plain-language health scores plus a personalized action plan. That matters because a wall of lab values means little if you cannot tell which ones need attention. A physician reviews your results, so you are not left to interpret abnormal flags alone.
What pushes Superpower ahead for longevity specifically is breadth at a reasonable price. You get the inflammation, metabolic, and hormone markers that researchers tie to healthy aging, not just a basic cholesterol and glucose snapshot. The catch worth knowing is that the AI concierge will suggest supplements, and those can add up if you say yes to everything, so keep the test and the upsell separate in your head.
Pricing: About $199 per year for most states ($399 in NY and NJ), HSA and FSA eligible.
Function Health – Best premium, clinician-reviewed membership
Function Health is the better choice if you want the deepest panel and a clinician reading every result. For around $365 a year it runs 160+ lab tests, then retests roughly 60 markers halfway through the year so you can see what changed.
Pros
- 160+ lab tests, the widest panel of any service here
- Two testing rounds a year, including a mid-year retest of key markers
- Clinician review with notes on every result, no per-test fees
- HSA and FSA eligible
Cons
- Costs nearly double Superpower at around $365 per year
- Premium add-ons like Galleri cancer screening cost extra
- The volume of data can feel overwhelming without guidance
Function recently dropped its membership to roughly $365 a year, down from $499, which narrows the gap with Superpower but still leaves it as the pricier option. What you pay extra for is depth and the reassurance of clinician sign-off. Every result comes with a clinician note, and the mid-year retest is genuinely useful if you are changing diet, training, or medication and want to confirm the numbers moved.
This is the service to choose when you treat your annual labs as a serious health project rather than a quick checkup. The 160+ test menu spans organ systems most basic panels skip, and the action plan, food guide, and supplement list give you a concrete next step. If you only want a once-a-year snapshot at the lowest price, Superpower is the smarter spend, but for two rounds and clinician depth, Function earns its premium.
Pricing: Around $365 per year, HSA and FSA eligible, optional add-ons priced separately.
Everlywell – Best for single targeted panels
Everlywell is the smart pick when you have one specific question, not a desire to track everything. Individual kits run from about $49 to $299 and ship to your door, so you can test thyroid, hormones, or metabolism without committing to an annual membership.
Pros
- Pay per kit, no yearly commitment, with prices from $49 to $299
- Focused panels for thyroid, hormones, metabolism, and food sensitivity
- Results processed through CLIA-certified labs
- Widely available, including through major retailers
Cons
- No single 100+ biomarker longevity panel like the membership services
- Buying several panels separately costs more than one full membership
- Less dashboard depth and ongoing tracking than Superpower or Function
Where the membership services give you breadth, Everlywell gives you precision and control over spend. If your doctor flagged your thyroid, or you want to check hormone levels before making a change, a single targeted kit answers that question for a fraction of an annual fee. The labs behind it are CLIA-certified, so the results carry clinical weight.
The tradeoff is that Everlywell is not built for comprehensive longevity tracking. There is no one-shot panel of 100+ markers, and if you find yourself buying three or four kits a year, a Superpower membership would likely cost less and give you more. Use Everlywell as a scalpel, not a dragnet.
Pricing: Individual kits from $49 to $299 depending on the panel.
SiPhox Health – Best for frequent low-cost retesting
SiPhox Health is built for people who want to retest often without a needle or a lab visit. Memberships start around $125 with a near-painless at-home collection device, fast 5 to 7 day turnaround, and HSA and FSA eligibility.
Pros
- Among the lowest cost per biomarker we found, starting around $125
- At-home collection with no clinic trip, plus a 5 to 7 day result window
- Flexible monthly, quarterly, or biannual retesting cadence
- HSA and FSA eligible
Cons
- Base panels cover fewer biomarkers than Superpower or Function
- Reaching 60 markers requires the Ultimate 360 upgrade at extra cost
- Best as a tracking tool rather than a one-time deep dive
The appeal of SiPhox is cadence. If you are actively working on metabolic or heart markers and want to see them move every quarter, paying for a full 100-plus panel each time is overkill. SiPhox lets you retest a focused set frequently and cheaply, which is exactly what behavior change needs: a tight feedback loop.
The collection itself uses an upper-arm device that most users describe as far less unpleasant than a venous draw, and results land in under a week. The honest limit is breadth. Base panels are smaller, and getting to 60 biomarkers means paying for the Ultimate 360 add-on. For a once-a-year longevity baseline, Superpower still wins on coverage, but for the person who lives in their numbers, SiPhox is the most affordable way to keep checking.
Pricing: Memberships from around $125, with an Ultimate 360 upgrade for roughly $100 more.
Why trust Vital Signs Today
We compared 12 at-home and longevity blood testing services and reviewed what each panel actually measures, not just the marketing headline biomarker count. We checked current 2026 pricing directly against each provider, separated membership fees from optional add-on upsells, and flagged where a cheaper one-off kit beats an annual plan. Our picks are based on coverage, value, and how usable the results are for a non-clinician.
How we picked
We scored each service against four criteria that matter for longevity testing specifically.
- Biomarker coverage: how many markers, and whether they include the metabolic, inflammation, and hormone panels tied to healthy aging.
- Value: total annual cost versus what you actually get, with upsells stripped out.
- Usability: whether results come with plain-language scores, an action plan, and clinician input.
- Convenience: at-home collection, turnaround time, and HSA or FSA eligibility.
Frequently asked questions
What is the best longevity blood test in 2026?
For most people, Superpower offers the best mix of coverage and price, screening 100+ biomarkers for around $199 a year. If you want the deepest panel with clinician review and two rounds a year, Function Health at about $365 is the premium alternative.
How much does a longevity blood test cost?
Annual memberships range from about $125 for SiPhox up to $365 for Function Health, with Superpower at roughly $199. Single-question kits from Everlywell start at $49, so cost depends on whether you want broad tracking or one targeted answer.
Are at-home longevity blood tests accurate?
The services here run samples through CLIA-certified labs, the same standard used by clinical labs. Accuracy depends on following the collection instructions carefully, especially for fasting markers, so read the kit directions before you draw your sample.
Can I use HSA or FSA funds to pay for these tests?
Yes. Superpower, Function Health, and SiPhox Health are all HSA and FSA eligible, which effectively lowers your cost by your tax rate. Many individual Everlywell kits qualify as well, though it is worth confirming at checkout.
Do I need a doctor to order a longevity blood test?
No. All four services let you order directly without a physician visit, and Superpower and Function include clinician or physician review of your results as part of the membership. You can then share the report with your own doctor if you choose.
The bottom line
If you want one yearly longevity baseline at the best price, choose Superpower for its 100+ biomarkers at around $199 and a dashboard that turns numbers into action. If budget is secondary and you want the deepest panel with clinician sign-off and a mid-year retest, Function Health at about $365 is worth the premium. For a single targeted question, an Everlywell kit costs far less than any membership, and if you want to retest cheaply every quarter, SiPhox Health is the most affordable feedback loop. Match the tool to the job and you will get more out of your results, and your money.
Sources
- Superpower official site and pricing: https://superpower.com/
- Superpower Blood Test Review 2026, Athletech News: https://athletechnews.com/superpower-blood-test-review/
- Function Health pricing page: https://www.functionhealth.com/pricing
- Function membership is now $365/year, Function Health: https://www.functionhealth.com/article/function365
- Everlywell Review 2026, Medical News Today: https://www.medicalnewstoday.com/articles/everlywell-review
- Everlywell products and pricing: https://www.everlywell.com/products/
- How much does SiPhox Health cost, SiPhox Health: https://siphoxhealth.com/articles/how-much-does-siphox-health-cost
- SiPhox Health official site: https://siphoxhealth.com/
