Disclosure: Vital Signs Today may earn a commission if you buy through links on this page, at no extra cost to you. This does not influence our evidence-based assessments. We are not a medical provider; talk to a clinician before acting on test results.
Quick answer: The Superpower biomarkers are roughly 100 measured blood markers (about 150 once you count calculated ratios) that map to plain health questions like “is my metabolism heading toward diabetes,” “are my hormones normal for my age,” and “are my liver and kidneys quietly under strain.” Superpower groups them into 17 plain-language health scores so a number you have never heard of (say, ApoB or HbA1c) becomes a verdict you can act on. For a yearly $199 baseline that tracks all of it over time and explains each result with an AI concierge, it is the easiest way to turn a wall of lab numbers into a clear picture of where your health actually stands.
Disclosure: Vital Signs Today may earn a commission if you buy through links on this page, at no extra cost to you. This does not influence our evidence-based assessments. We are not a medical provider; talk to a clinician before acting on test results.
| Service | Best for | Pricing | Visit |
|---|---|---|---|
| Superpower | Whole-body optimization | ~$179/yr membership | View › |
What “100+ Superpower biomarkers” actually means
A biomarker is just a measurable signal in your blood that says something about how a system in your body is working. Cholesterol is a biomarker. So is blood sugar, vitamin D, and your thyroid hormone. On its own, one number is almost useless. The value of the Superpower biomarker test is that it pulls about 100 of them in a single annual draw, then about 150 counting calculated ratios, so you see how the systems interact instead of chasing one marker at a time.
Here is the part most lab reports get wrong: a column of numbers with reference ranges does not tell a normal person anything. Superpower’s answer is to translate the panel into 17 health scores plus a personalized action plan, and to give you an AI concierge you can literally ask “why is my ApoB flagged” in plain English. That translation layer, not the raw marker count, is the actual product.
One honest caveat up front: this is a screening and tracking service, not a diagnostic clinic. It is excellent at telling you where to look. It does not replace a doctor, and any result outside the normal range should be reviewed with a clinician before you change anything.
The Superpower biomarkers, grouped by the question they answer
Instead of listing markers alphabetically, the useful way to read a panel this size is by the health question each cluster answers. That is also how Superpower’s scores are organized. Below is how the biomarker groups break down and why each one earns its place in a yearly baseline.
Metabolic health: am I heading toward diabetes?
This is the cluster most worth your attention, because metabolic dysfunction is common, silent, and reversible if you catch it early. Key markers here include fasting glucose, HbA1c (your three-month average blood sugar), fasting insulin, and calculated insulin resistance. Insulin is the early-warning marker most standard checkups skip: it often climbs years before glucose does, so testing it is how you spot trouble while it is still fixable.
Reading these together is the point. A normal glucose with a high insulin tells a very different story than both being normal, and you only catch that contrast on a panel that runs the full metabolic group at once.
Cardiovascular risk: what is my heart actually facing?
A standard cholesterol panel gives you total cholesterol, LDL, HDL, and triglycerides. The Superpower biomarker test goes a layer deeper with markers that better predict real risk: ApoB (the count of artery-clogging particles, now considered a sharper risk signal than LDL), Lp(a) (a largely genetic risk factor you test once in your life), and hs-CRP (a measure of inflammation). If your family has heart disease, the ApoB and Lp(a) results alone can change how seriously you and your doctor take prevention.
Hormones: are my levels normal for my age and goals?
The hormone group covers thyroid (TSH, free T3, free T4), sex hormones (testosterone, estradiol, and related markers), and stress and metabolic hormones. Thyroid in particular is a frequent culprit behind unexplained fatigue, weight changes, and brain fog, and it is the kind of thing people chase for months without testing. Seeing the hormone panel in one view makes it easier to connect a symptom to a likely cause.
Organ function: are my liver and kidneys under strain?
This group quietly does a lot of work. Liver enzymes (ALT, AST), kidney markers (creatinine and calculated eGFR), and electrolytes flag organ stress long before you would ever feel it. These are also the markers that catch side effects of medications, heavy training, or alcohol load, which is exactly the kind of slow drift a once-a-year baseline is built to surface.
Blood, iron, and inflammation: why am I so tired?
Fatigue is the number-one reason people order bloodwork, and the answer usually lives in this group. A complete blood count (CBC), a full iron panel including ferritin (your iron stores), plus B12 and folate cover the most common fixable causes of low energy. Iron deficiency in particular is widespread and easy to miss because a basic checkup often skips ferritin entirely.
Vitamins and nutrients: am I missing something basic?
Vitamin D, B12, folate, magnesium, and other micronutrient markers round out the panel. These are unglamorous but high-yield: a vitamin D or B12 deficiency is cheap to fix and can meaningfully change how you feel, yet most people have never had either measured. Catching a flat-out deficiency here is one of the most concrete payoffs of full-panel testing.
Why the 17 health scores matter more than the marker count
It is tempting to shop these services on raw biomarker count, the way you would compare megapixels on a camera. That is the wrong lens. A list of 100+ Superpower biomarkers is only useful if you can understand it, and a flagged number you do not understand just becomes anxiety.
Superpower’s 17 plain-language health scores roll the underlying markers up into categories like metabolic, heart, hormones, and so on, each with a clear status and a personalized action plan. The AI concierge then lets you interrogate any result in conversation. That is the difference between “your homocysteine is 14” and “your homocysteine is elevated, here is what it means and what to do next.” For most people, that interpretation layer is what turns a blood test into a decision.
Full-body lab membership: 100+ biomarkers, doctor-reviewed, tracked over time.
How Superpower’s biomarker panel compares to other testing routes
The Superpower biomarker test is not the only way to get this data. Here is an honest read on where it fits against the main alternatives, so you can pick by what you actually need.
Function Health
Function Health is the closest comparison and, frankly, the more clinically thorough one. It runs 160+ biomarkers for $365 per year, includes two draws per year plus a urinalysis and a 6-month retest, which means more data points and tighter tracking across the year. The tradeoff is price and a newer AI chat experience. If you want the deepest possible workup and do not mind paying more, Function is a strong pick.
Superpower
Superpower covers the same core ground (100+ markers, about 150 with ratios) for $199 per year with one comprehensive annual draw, 17 health scores, an action plan, and the AI concierge. Note that it is $399 in New York and New Jersey because of state lab rules. The reason we lean toward it for most readers is simple: it hits the markers that matter, it is roughly half the price, and the score-plus-concierge translation makes the results genuinely usable rather than just abundant. For a first full-body baseline, that combination is hard to beat.
Everlywell
If you only care about one or two specific markers (say, you just want ferritin or thyroid checked), a full membership is overkill. Everlywell sells at-home, single-marker test kits run through CLIA-certified labs with per-kit pricing and online results. It is the right tool when your question is narrow and targeted, not “show me everything.” The flip side: buy three or four of those kits and you are usually past the price of a full Superpower panel, with none of the cross-marker context.
SiPhox Health
SiPhox Health offers at-home blood testing with a finger-prick option and longevity-focused panels. If a needle and a draw appointment are the thing stopping you from testing at all, the finger-prick convenience is a real advantage. The tradeoff is breadth: a finger-prick sample supports a narrower set of markers than a full venous draw like Superpower’s.
How to actually use your Superpower biomarker results
Getting 100+ markers is step one. Using them is the part that pays off. A simple approach: read the 17 scores first to see which systems are flagged, then drill into the specific biomarkers behind any red score, and use the AI concierge to understand what each one means before you act. Anything outside the normal range is a conversation to have with a clinician, not a self-diagnosis.
The real long-game value is the trendline. One blood test is a snapshot. A yearly draw turns your biomarkers into a movie, so you can see whether a lifestyle change actually moved ApoB or HbA1c instead of guessing. That is the case for a tracking membership over a one-and-done test.
Related reading on Vital Signs Today
- Superpower At-Home Blood Test: How the Draw and Locations Work
- What Is the Superpower Blood Test? A Plain-English Guide
- The ‘Superhuman’ Blood Test: What People Actually Mean (and the Best Option)
- Superpower Blood Test Review (2026): Is It Worth the Membership?
Frequently asked questions
How many biomarkers does Superpower test?
Superpower measures 100+ biomarkers, or about 150 once you include calculated ratios, in a single comprehensive annual blood draw. These cover metabolic, cardiovascular, hormone, organ, blood, and nutrient markers, and they are summarized into 17 plain-language health scores so the Superpower biomarkers are actually readable rather than just numerous.
What does the Superpower biomarker test tell you that a normal checkup doesn’t?
A typical annual physical often runs a basic metabolic panel, a CBC, and a standard cholesterol panel. The Superpower biomarker test adds markers your doctor frequently skips unless you ask, including fasting insulin, ApoB, Lp(a), hs-CRP, full iron studies with ferritin, and a broad hormone and vitamin panel. Those are the markers that tend to catch problems early.
Which Superpower biomarkers matter most?
It depends on your goal, but the highest-yield groups for most adults are the metabolic markers (glucose, HbA1c, fasting insulin), the advanced cardiovascular markers (ApoB, Lp(a), hs-CRP), and the fatigue panel (ferritin, B12, vitamin D, thyroid). These cluster around the most common silent and fixable issues, which is why they anchor a full-body baseline.
Is the Superpower biomarker test a diagnosis?
No. Superpower is a screening and tracking service, not a diagnostic clinic. It tells you where your numbers stand and where to look, but any result outside the normal range should be reviewed with a clinician who can order follow-up testing and make an actual diagnosis. Treat the panel as a map, not a verdict.
How much does the Superpower biomarker test cost?
Superpower is $199 per year for the membership, which includes the comprehensive annual draw, the 100+ biomarkers, the 17 health scores, the action plan, and the AI concierge. It is $399 in New York and New Jersey due to state lab rules. By comparison, Function Health runs $365 per year for 160+ biomarkers with two draws and a mid-year retest.
